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A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm

<p>Abstract</p> <p>Background</p> <p>Intrabodies are defined as antibody molecules which are ectopically expressed inside the cell. Such intrabodies can be used to visualize or inhibit the targeted antigen in living cells. However, most antibody fragments cannot be used as intrabodies because they d...

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Bibliografische Detailangaben
Hauptverfasser: Saven Jeffery G, Larroque Christian, Bec Nicole, Sibler Annie-Paule, Wang Wei, Stoessel Audrey, Philibert Pascal, Courtête Jérôme, Weiss Etienne, Martineau Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2007-11-01
Schriftenreihe:BMC Biotechnology
Online-Zugang:http://www.biomedcentral.com/1472-6750/7/81
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