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A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm

<p>Abstract</p> <p>Background</p> <p>Intrabodies are defined as antibody molecules which are ectopically expressed inside the cell. Such intrabodies can be used to visualize or inhibit the targeted antigen in living cells. However, most antibody fragments cannot be used as intrabodies because they d...

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Autori principali: Saven Jeffery G, Larroque Christian, Bec Nicole, Sibler Annie-Paule, Wang Wei, Stoessel Audrey, Philibert Pascal, Courtête Jérôme, Weiss Etienne, Martineau Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2007-11-01
Serie:BMC Biotechnology
Accesso online:http://www.biomedcentral.com/1472-6750/7/81
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