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Design of live-attenuated animal vaccines based on pseudorabies virus platform

Abstract Pseudorabies virus (PRV) is a double-stranded DNA virus with a genome approximating 150 kb in size. PRV contains many non-essential genes that can be replaced with genes encoding heterogenous antigens without affecting viral propagation. With the ability to induce cellular, humoral and muco...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Zhen Liu, Zhengjie Kong, Meng Chen, Yingli Shang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-05-01
Schriftenreihe:Animal Diseases
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Online-Zugang:https://doi.org/10.1186/s44149-022-00044-w
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