Design of live-attenuated animal vaccines based on pseudorabies virus platform

Abstract Pseudorabies virus (PRV) is a double-stranded DNA virus with a genome approximating 150 kb in size. PRV contains many non-essential genes that can be replaced with genes encoding heterogenous antigens without affecting viral propagation. With the ability to induce cellular, humoral and muco...

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Detalhes bibliográficos

Principais autores:	Zhen Liu, Zhengjie Kong, Meng Chen, Yingli Shang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-05-01
coleção:	Animal Diseases
Assuntos:	Recombinant pseudorabies virus Live-attenuated vaccine Swine CRISPR/Cas9
Acesso em linha:	https://doi.org/10.1186/s44149-022-00044-w
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