Construction of pseudorabies virus variant attenuated vaccine: codon deoptimization of US3 and UL56 genes based on PRV gE/TK deletion strain

Since 2011, pseudorabies based on the pseudorabies virus (PRV) variant has emerged as a serious health issue in pig farms in China. The PRV gE/TK or gE/gI/TK deletion strains protect against emerging PRV variants. However, these variants may cause lethal infections in newborn piglets without PRV ant...

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Xehetasun bibliografikoak

Egile Nagusiak:	Mengwei Xu, Laixu Zhu, Aimin Ge, Yamei Liu, Saisai Chen, Ziwen Wei, Yating Zheng, Ling Tong, Zhisheng Wang, Rongmei Fei, Jichun Wang, Chuanjian Zhang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2023-10-01
Saila:	Frontiers in Microbiology
Gaiak:	pseudorabies virus attenuation immunogenicity codon deoptimization US3-S UL56
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1248573/full
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