Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Abstract Dysregulated tissue‐resident macrophages (TRMs) contribute to the pathogenesis of inflammatory bowel disease (IBD) and multiple sclerosis (MS). Uncovering molecular regulators of the divergent role of TRMs in inflammation can advance therapeutic strategies for autoimmune disorders. Here, a...

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Egile Nagusiak:	Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Wiley 2026-02-01
Saila:	Advanced Science
Gaiak:	autoimmune diseases inflammatory bowel disease p‐TBK1 tissue‐resident macrophages ubiquitination
Sarrera elektronikoa:	https://doi.org/10.1002/advs.202504930
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!