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The HDAC Inhibitor Phenylbutyrate Reverses Effects of Neonatal Ventral Hippocampal Lesion in Rats

Recent evidence suggests that epigenetic mechanisms play a role in psychiatric diseases. In this study, we considered rats with neonatal ventral hippocampal lesions (NVHL) that are currently used for modeling neurodevelopmental aspects of schizophrenia. Contribution of epigenetic regulation to the e...

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Autores principales: Guy eSandner, Lionel eHost, Marie-Josée eAngst, Thierry eGuiberteau, Blandine eGuignard, Jean eZwiller
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2011-01-01
Colección:Frontiers in Psychiatry
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Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00153/full
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