The HDAC Inhibitor Phenylbutyrate Reverses Effects of Neonatal Ventral Hippocampal Lesion in Rats

Recent evidence suggests that epigenetic mechanisms play a role in psychiatric diseases. In this study, we considered rats with neonatal ventral hippocampal lesions (NVHL) that are currently used for modeling neurodevelopmental aspects of schizophrenia. Contribution of epigenetic regulation to the e...

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Principais autores:	Guy eSandner, Lionel eHost, Marie-Josée eAngst, Thierry eGuiberteau, Blandine eGuignard, Jean eZwiller
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2011-01-01
叢編:	Frontiers in Psychiatry
主題:	Epigenetic regulation Animal model of schizophrenia Brain ontogenesis Histone deacetylase inhibitor Ventral hippocampal lesion
在線閱讀:	http://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00153/full
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