Bacterial killing by complement requires direct anchoring of membrane attack complex precursor C5b-7.
An important effector function of the human complement system is to directly kill Gram-negative bacteria via Membrane Attack Complex (MAC) pores. MAC pores are assembled when surface-bound convertase enzymes convert C5 into C5b, which together with C6, C7, C8 and multiple copies of C9 forms a transm...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2020-06-01
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| Reeks: | PLoS Pathogens |
| Online toegang: | https://doi.org/10.1371/journal.ppat.1008606 |
| Tags: |
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