Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation

Objective: Tyloxapol is a non-ionic surfactant with diverse pharmacological effects including anti-inflammatory, anti-malignant tumor and antioxidant activities. However, the effect of tyloxapol on osteoclastogenesis has not been elucidated. In this study, we intended to clarify the effect of tyloxa...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Wen Guo, Haijun Li, Yan Lou, Yue Zhang, Jia Wang, Ming Qian, Haifeng Wei, Jianru Xiao, Youjia Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-05-01
coleção:	Journal of Orthopaedic Translation
Assuntos:	Tyloxapol Osteoporosis Osteoclast Osteoblast Nuclear factor kappa-B (NF-κB) Mitogen-activated protein kinase (MAPK)
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2214031X21000061
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!