Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation

Objective: Tyloxapol is a non-ionic surfactant with diverse pharmacological effects including anti-inflammatory, anti-malignant tumor and antioxidant activities. However, the effect of tyloxapol on osteoclastogenesis has not been elucidated. In this study, we intended to clarify the effect of tyloxa...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Wen Guo, Haijun Li, Yan Lou, Yue Zhang, Jia Wang, Ming Qian, Haifeng Wei, Jianru Xiao, Youjia Xu
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2021-05-01
Σειρά:	Journal of Orthopaedic Translation
Θέματα:	Tyloxapol Osteoporosis Osteoclast Osteoblast Nuclear factor kappa-B (NF-κB) Mitogen-activated protein kinase (MAPK)
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2214031X21000061
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