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Conformationally Restricted Oligonucleotide Analogues 'Made in Bern': A Mini Review

In our search for novel oligonucleotide analogues for use in therapy and DNA-based diagnostics we explored the concept of conformational preorganization as a means to improve duplex stability with complementary DNA and RNA. This research effort has led to a number of novel DNA analogues an...

詳細記述

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書誌詳細
第一著者: Christian J. Leumann
フォーマット: Artigo
言語:Alemão
出版事項: Swiss Chemical Society 2001-12-01
シリーズ:CHIMIA
主題:
オンライン・アクセス:https://www.chimia.ch/chimia/article/view/3534
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