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Conformationally Restricted Oligonucleotide Analogues 'Made in Bern': A Mini Review

In our search for novel oligonucleotide analogues for use in therapy and DNA-based diagnostics we explored the concept of conformational preorganization as a means to improve duplex stability with complementary DNA and RNA. This research effort has led to a number of novel DNA analogues an...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Kaituhi matua: Christian J. Leumann
Hōputu: Artigo
Reo:Alemão
I whakaputaina: Swiss Chemical Society 2001-12-01
Rangatū:CHIMIA
Ngā marau:
Urunga tuihono:https://www.chimia.ch/chimia/article/view/3534
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