Conformationally Restricted Oligonucleotide Analogues 'Made in Bern': A Mini Review
In our search for novel oligonucleotide analogues for use in therapy and DNA-based diagnostics we explored the concept of conformational preorganization as a means to improve duplex stability with complementary DNA and RNA. This research effort has led to a number of novel DNA analogues an...
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| Format: | Artigo |
| Sprog: | Alemão |
| Udgivet: |
Swiss Chemical Society
2001-12-01
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| Serier: | CHIMIA |
| Fag: | |
| Online adgang: | https://www.chimia.ch/chimia/article/view/3534 |
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