Quantification of transcriptome changes to investigate the role of glucocorticoid receptor-RNA binding during dexamethasone treatment

Abstract Objectives The glucocorticoid receptor (GR) is a well-studied, ligand-activated transcription factor and a common target of anti-inflammatory treatments. Recently, several studies have drawn attention the effects of binding of GR to RNA rather than DNA and the potential implications of this...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Nickolaus C. Lammer, Mary A. Allen, Robert T. Batey, Deborah S. Wuttke
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-08-01
Edice:	BMC Research Notes
Témata:	Transcription factor Glucocorticoid receptor RNA binding RNA sequencing Transcriptomics 4-thiouridine
On-line přístup:	https://doi.org/10.1186/s13104-023-06446-4
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!