Quantification of transcriptome changes to investigate the role of glucocorticoid receptor-RNA binding during dexamethasone treatment

Abstract Objectives The glucocorticoid receptor (GR) is a well-studied, ligand-activated transcription factor and a common target of anti-inflammatory treatments. Recently, several studies have drawn attention the effects of binding of GR to RNA rather than DNA and the potential implications of this...

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Váldodahkkit:	Nickolaus C. Lammer, Mary A. Allen, Robert T. Batey, Deborah S. Wuttke
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2023-08-01
Ráidu:	BMC Research Notes
Fáttát:	Transcription factor Glucocorticoid receptor RNA binding RNA sequencing Transcriptomics 4-thiouridine
Liŋkkat:	https://doi.org/10.1186/s13104-023-06446-4
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