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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

Abstract There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer (EOC) is largely unknown. Here, we inves...

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Bibliografiska uppgifter
Huvudupphov: Andrew J. McKenzie, Stephanie R. Hicks, Kathryn V. Svec, Hannah Naughton, Zöe L. Edmunds, Alan K. Howe
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2018-05-01
Serie:Scientific Reports
Länkar:https://doi.org/10.1038/s41598-018-25589-0
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