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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

Abstract There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer (EOC) is largely unknown. Here, we inves...

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Principais autores: Andrew J. McKenzie, Stephanie R. Hicks, Kathryn V. Svec, Hannah Naughton, Zöe L. Edmunds, Alan K. Howe
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2018-05-01
Serija:Scientific Reports
Online dostop:https://doi.org/10.1038/s41598-018-25589-0
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