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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

Abstract There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer (EOC) is largely unknown. Here, we inves...

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Autors principals: Andrew J. McKenzie, Stephanie R. Hicks, Kathryn V. Svec, Hannah Naughton, Zöe L. Edmunds, Alan K. Howe
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2018-05-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-018-25589-0
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