Dopaminergic REST is implicated in the tamoxifen-induced neuroprotection against manganese toxicity in female mice
IntroductionChronic manganese (Mn) overexposure causes manganism, a Parkinson’s disease-like neurological disorder, due to its preferential accumulation in the basal ganglia. Tamoxifen (TX), a selective estrogen receptor modulator (SERM), afforded neuroprotection against Mn toxicity, and RE1-silenci...
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| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Frontiers Media S.A.
2025-10-01
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| Σειρά: | Frontiers in Pharmacology |
| Θέματα: | |
| Διαθέσιμο Online: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1627400/full |
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