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Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma

BackgroundGlioblastoma (GBM) is the most aggressive primary malignancy of the central nervous system, characterized by profound heterogeneity and an immunosuppressive microenvironment, leading to dismal prognosis. Pyroptosis, an inflammatory form of programmed cell death, has been increasingly linke...

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Bibliografiske detaljer
Principais autores: Liren Fang, Desheng Wang, Fanlei Meng, Yinzhi Wang, Lu Feng, Hong Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1693940/full
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