Construction of a macrophage-related prognostic signature and assessment of immune checkpoint inhibitor efficacy of HCC

Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death, with limited treatment options and high recurrence rates. Prognostic biomarkers and predictors of immune checkpoint inhibitor (ICI) response are urgently needed. This study aimed to develop a macrophage-related gene...

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Autores principales:	Shouge Zang, Hongwei Chen, Yuqian Han, Di Cui, Jiangtao Yu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-07-01
Colección:	Scientific Reports
Materias:	Hepatocellular carcinoma Tumor-associated macrophages Single-cell sequencing Immune checkpoint inhibitors Prognostic signature PLAUR
Acceso en línea:	https://doi.org/10.1038/s41598-025-06937-3
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