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Cross-validated stepwise regression for identification of novel non-nucleoside reverse transcriptase inhibitor resistance associated mutations

<p>Abstract</p> <p>Background</p> <p>Linear regression models are used to quantitatively predict drug resistance, the phenotype, from the HIV-1 viral genotype. As new antiretroviral drugs become available, new resistance pathways emerge and the number of resistance associated mutations continues to...

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Autores principales: Van Houtte Margriet, Lecocq Pierre, Van Craenenbroeck Elke, Van der Borght Koen, Van Kerckhove Barbara, Bacheler Lee, Verbeke Geert, van Vlijmen Herman
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2011-10-01
Colección:BMC Bioinformatics
Acceso en línea:http://www.biomedcentral.com/1471-2105/12/386
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