Cross-validated stepwise regression for identification of novel non-nucleoside reverse transcriptase inhibitor resistance associated mutations

<p>Abstract</p> <p>Background</p> <p>Linear regression models are used to quantitatively predict drug resistance, the phenotype, from the HIV-1 viral genotype. As new antiretroviral drugs become available, new resistance pathways emerge and the number of resistance associated mutations continues to...

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Detalhes bibliográficos

Principais autores:	Van Houtte Margriet, Lecocq Pierre, Van Craenenbroeck Elke, Van der Borght Koen, Van Kerckhove Barbara, Bacheler Lee, Verbeke Geert, van Vlijmen Herman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2011-10-01
coleção:	BMC Bioinformatics
Acesso em linha:	http://www.biomedcentral.com/1471-2105/12/386
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