COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
Metabolic engineering requires the balancing of gene expression to obtain optimal output. Here the authors present COMPASS – COMbinatorial Pathway ASSembly – which uses plant-derived artificial transcription factors and cloning of thousands of DNA constructs in parallel to rapidly optimise pathways.
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2019-06-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-019-10224-x |
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