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COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors

Metabolic engineering requires the balancing of gene expression to obtain optimal output. Here the authors present COMPASS – COMbinatorial Pathway ASSembly – which uses plant-derived artificial transcription factors and cloning of thousands of DNA constructs in parallel to rapidly optimise pathways.

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Gita Naseri, Jessica Behrend, Lisa Rieper, Bernd Mueller-Roeber
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2019-06-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-019-10224-x
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