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COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors

Metabolic engineering requires the balancing of gene expression to obtain optimal output. Here the authors present COMPASS – COMbinatorial Pathway ASSembly – which uses plant-derived artificial transcription factors and cloning of thousands of DNA constructs in parallel to rapidly optimise pathways.

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Detalles Bibliográficos
Principais autores: Gita Naseri, Jessica Behrend, Lisa Rieper, Bernd Mueller-Roeber
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2019-06-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-019-10224-x
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