Sensitive and reliable detection of Kit point mutation Asp 816 to Val in pathological material
<p>Abstract</p> <p>Background</p> <p>Human mastocytosis is a heterogenous disorder which is linked to a gain-of-function mutation in the kinase domain of the receptor tyrosine kinase Kit. This D816V mutation leads to constitutive activation and phosphorylation of Kit with proliferative disorders of...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2007-09-01
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| Edice: | Diagnostic Pathology |
| On-line přístup: | http://www.diagnosticpathology.org/content/2/1/37 |
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