Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

Persistent dysregulation of IL-6 production and signaling have been implicated in the pathology of various cancers. In systemic mastocytosis, increased serum levels of IL-6 associate with disease severity and progression, although the mechanisms involved are not well understood. Since systemic masto...

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Auteurs principaux:	Araceli Tobío, Geethani Bandara, Denise A. Morris, Do-Kyun Kim, Michael P. O’Connell, Hirsh D. Komarow, Melody C. Carter, Daniel Smrz, Dean D. Metcalfe, Ana Olivera
Format:	Artigo
Langue:	Inglês
Publié:	Ferrata Storti Foundation 2020-01-01
Collection:	Haematologica
Accès en ligne:	https://haematologica.org/article/view/9482
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