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Structural studies of the phosphoribosyltransferase involved in cobamide biosynthesis in methanogenic archaea and cyanobacteria

Abstract Cobamides (Cbas) are coenzymes used by cells across all domains of life, but de novo synthesis is only found in some bacteria and archaea. Five enzymes assemble the nucleotide loop in the alpha phase of the corrin ring. Condensation of the activated ring and nucleobase yields adenosyl-Cba 5...

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Autors principals: Victoria L. Jeter, Anne H. Schwarzwalder, Ivan Rayment, Jorge C. Escalante-Semerena
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2022-10-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-022-21765-5
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