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Structural studies of the phosphoribosyltransferase involved in cobamide biosynthesis in methanogenic archaea and cyanobacteria

Abstract Cobamides (Cbas) are coenzymes used by cells across all domains of life, but de novo synthesis is only found in some bacteria and archaea. Five enzymes assemble the nucleotide loop in the alpha phase of the corrin ring. Condensation of the activated ring and nucleobase yields adenosyl-Cba 5...

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Principais autores: Victoria L. Jeter, Anne H. Schwarzwalder, Ivan Rayment, Jorge C. Escalante-Semerena
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2022-10-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-022-21765-5
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