IAR025, a novel anti-DLL3 x CD3-bispecific antibody, displays high antitumor efficacy in preclinical models of small-cell lung cancer
Abstract Small-cell lung cancer (SCLC) is one of the most aggressive subtype of lung carcinoma with limited treatment options. Delta-like ligand 3 (DLL3), a Notch ligand protein, has been an attractive target for SCLC due to its high expression on SCLC but limited expression on normal tissues. Here,...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Springer
2026-05-01
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| سلاسل: | Cancer Immunology, Immunotherapy |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1007/s00262-026-04416-w |
| الوسوم: |
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