αTrop2/αCD3 bispecific protein engager-armed T cells (BATs) exhibit potent antitumor activity against nasopharyngeal carcinoma

Abstract Nasopharyngeal carcinoma (NPC) remains a highly aggressive malignancy with poor outcomes in advanced and recurrent disease. Although immune checkpoint inhibitors combined with chemotherapy improve survival, many patients still experience relapse or disease progression. Here, we developed a...

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Autori principali:	Kwanpirom Suwanchiwasiri, Chalermchai Somboonpatarakun, Nan Chaiyariti, Utid Suriya, Surang Chankhamhaengdecha, Pa‑thai Yenchitsomanus, Tavan Janvilisri, Mutita Junking
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2026-05-01
Serie:	Cancer Immunology, Immunotherapy
Soggetti:	Bispecific protein engager Bispecific protein engager-armed T cells Cancer immunotherapy Trop2 Nasopharyngeal carcinoma
Accesso online:	https://doi.org/10.1007/s00262-026-04406-y
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