αTrop2/αCD3 bispecific protein engager-armed T cells (BATs) exhibit potent antitumor activity against nasopharyngeal carcinoma

Abstract Nasopharyngeal carcinoma (NPC) remains a highly aggressive malignancy with poor outcomes in advanced and recurrent disease. Although immune checkpoint inhibitors combined with chemotherapy improve survival, many patients still experience relapse or disease progression. Here, we developed a...

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Detalhes bibliográficos

Principais autores:	Kwanpirom Suwanchiwasiri, Chalermchai Somboonpatarakun, Nan Chaiyariti, Utid Suriya, Surang Chankhamhaengdecha, Pa‑thai Yenchitsomanus, Tavan Janvilisri, Mutita Junking
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-05-01
coleção:	Cancer Immunology, Immunotherapy
Assuntos:	Bispecific protein engager Bispecific protein engager-armed T cells Cancer immunotherapy Trop2 Nasopharyngeal carcinoma
Acesso em linha:	https://doi.org/10.1007/s00262-026-04406-y
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