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CD89-mediated recruitment of macrophages via a bispecific antibody enhances anti-tumor efficacy

Since tumors are often infiltrated by macrophages, it would be advantageous to turn these types of cells into cytotoxic effector cells. Here, we have designed a novel bispecific antibody (BsAb) that targets both tumor antigen (CD20) and the FcαRI receptor (CD89). This antibody could be used to lyse...

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Bibliográfalaš dieđut
Váldodahkkit: Bingyu Li, Lijun Xu, Chenyu Pi, Yanxin Yin, Kun Xie, Fei Tao, Renhao Li, Hua Gu, Jianmin Fang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Taylor & Francis Group 2018-01-01
Ráidu:OncoImmunology
Fáttát:
Liŋkkat:http://dx.doi.org/10.1080/2162402X.2017.1380142
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