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Impact of Administration Time Errors on Clearance Estimation in Pharmacokinetic Analyses

ABSTRACT This study aimed to comprehensively assess the impact of administration time errors on the estimation of clearance (CL), a key pharmacokinetic (PK) parameter used to predict appropriate maintenance dosing and drug exposure. To identify general principles, we simulated 23 cases of hypothetic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Katsukuni Fujimoto, Kazuhiko Asari, Kiyoshi Mihara
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley 2025-12-01
Cyfres:Clinical and Translational Science
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1111/cts.70448
Tagiau: Ychwanegu Tag
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