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Impact of Administration Time Errors on Clearance Estimation in Pharmacokinetic Analyses

ABSTRACT This study aimed to comprehensively assess the impact of administration time errors on the estimation of clearance (CL), a key pharmacokinetic (PK) parameter used to predict appropriate maintenance dosing and drug exposure. To identify general principles, we simulated 23 cases of hypothetic...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Katsukuni Fujimoto, Kazuhiko Asari, Kiyoshi Mihara
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wiley 2025-12-01
Sraith:Clinical and Translational Science
Ábhair:
Rochtain ar líne:https://doi.org/10.1111/cts.70448
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