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Celastrol and Triptolide Suppress Stemness in Triple Negative Breast Cancer: Notch as a Therapeutic Target for Stem Cells

Triple negative breast cancer (TNBC) is observed in ~15% of breast cancers and results in poor survival and increased distant metastases. Within the tumor are present a small portion of cancer stem cells that drive tumorigenesis and metastasis. In this study, we aimed to elucidate whether the two na...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Prabhu Ramamoorthy, Prasad Dandawate, Roy A. Jensen, Shrikant Anant
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2021-04-01
Saila:Biomedicines
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/2227-9059/9/5/482
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