Polymerization of C9 enhances bacterial cell envelope damage and killing by membrane attack complex pores
Complement proteins can form membrane attack complex (MAC) pores that directly kill Gram-negative bacteria. MAC pores assemble by stepwise binding of C5b, C6, C7, C8 and finally C9, which can polymerize into a transmembrane ring of up to 18 C9 monomers. It is still unclear if the assembly of a polym...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science (PLoS)
2021-11-01
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| Schriftenreihe: | PLoS Pathogens |
| Online-Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604303/?tool=EBI |
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