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Co-culture with fibroblasts in stiff 3D scaffolds increases CD54 and CD140a expression on macrophages

Vascular fibrosis is a major contributor to hypertension and cardiovascular disease and is caused by excessive extracellular matrix deposition and tissue stiffening. Macrophages and fibroblasts are key regulators of this process, yet most studies have relied on non-physiological two-dimensional (2D)...

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Bibliografische gegevens
Hoofdauteurs: Jennessa WX Ng, Santosh TRB Rao, Emily H. Field, Kaitlyn Ritchie, Mark D. Wright, Nicholas P. Reynolds, Sean W. Cutter, Katrina J. Binger
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2026-06-01
Reeks:Frontiers in Immunology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1771248/full
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