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Tau phosphorylation by GSK-3β promotes tangle-like filament morphology

<p>Abstract</p> <p>Background</p> <p>Neurofibrillary tangles (NFTs) are intraneuronal aggregates associated with several neurodegenerative diseases including Alzheimer's disease. These abnormal accumulations are primarily comprised of fibrils of the microtubule-associated protein tau. During the pro...

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書誌詳細
主要な著者: Gamblin Truman C, Sun Qian, Rankin Carolyn A
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2007-06-01
シリーズ:Molecular Neurodegeneration
オンライン・アクセス:http://www.molecularneurodegeneration.com/content/2/1/12
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