Inhibition of the Self-Assembly of Aβ and of Tau by Polyphenols: Mechanistic Studies

The amyloid-β (Aβ) peptide and tau protein are thought to play key neuropathogenic roles in Alzheimer’s disease (AD). Both Aβ and tau self-assemble to form the two major pathological hallmarks of AD: amyloid plaques and neurofibrillary tangles, respectively. In this review, we s...

Whakaahuatanga katoa

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Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua:	Qiuchen Zheng, Micheal T. Kebede, Merc M. Kemeh, Saadman Islam, Bethany Lee, Stuart D. Bleck, Liliana A. Wurfl, Noel D. Lazo
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2019-06-01
Rangatū:	Molecules
Ngā marau:	Alzheimer′s disease amyloid-β self-assembly tau self-assembly tau hyperphosphorylation amyloid assemblies neurofibrillary tangles polyphenols
Urunga tuihono:	https://www.mdpi.com/1420-3049/24/12/2316
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Inhibition of the Self-Assembly of Aβ and of Tau by Polyphenols: Mechanistic Studies

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