Inhibition of the Self-Assembly of Aβ and of Tau by Polyphenols: Mechanistic Studies

The amyloid-β (Aβ) peptide and tau protein are thought to play key neuropathogenic roles in Alzheimer’s disease (AD). Both Aβ and tau self-assemble to form the two major pathological hallmarks of AD: amyloid plaques and neurofibrillary tangles, respectively. In this review, we s...

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Bibliografiska uppgifter

Huvudupphov:	Qiuchen Zheng, Micheal T. Kebede, Merc M. Kemeh, Saadman Islam, Bethany Lee, Stuart D. Bleck, Liliana A. Wurfl, Noel D. Lazo
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2019-06-01
Serie:	Molecules
Ämnen:	Alzheimer′s disease amyloid-β self-assembly tau self-assembly tau hyperphosphorylation amyloid assemblies neurofibrillary tangles polyphenols
Länkar:	https://www.mdpi.com/1420-3049/24/12/2316
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