Immune Tolerance to Tumor Antigens Occurs in a Specialized Environment of the Spleen

Peripheral tolerance to tumor antigens (Ags) is a major hurdle for antitumor immunity. Draining lymph nodes are considered the privileged sites for Ag presentation to T cells and for the onset of peripheral tolerance. Here, we show that the spleen is fundamentally important for tumor-induced toleran...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Stefano Ugel, Elisa Peranzoni, Giacomo Desantis, Mariacristina Chioda, Steffen Walter, Toni Weinschenk, Jordi C. Ochando, Anna Cabrelle, Susanna Mandruzzato, Vincenzo Bronte
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2012-09-01
Цуврал:	Cell Reports
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2211124712002318
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!