Lower expression of neuronal isoform in vulnerable excitatory neurons increases risk in Alzheimer's disease
Background: Neurons in Alzheimer's disease (AD) experience elevated DNA damage, with DNA repair sites enriched at enhancer regions of genes essential for neuronal survival. Excitatory neurons in the cortical superficial layers expressing CUX2 and RORB (Cux2+/Rorb+), are selectively vulnerable in AD...
Furkejuvvon:
| Váldodahkkit: | , , , , |
|---|---|
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
SAGE Publishing
2025-01-01
|
| Ráidu: | Journal of Alzheimer's Disease Reports |
| Liŋkkat: | https://doi.org/10.1177/25424823241296018 |
| Fáddágilkorat: |
Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!
|