A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus <named-content content-type="genus-species">Aspergillus fumigatus</named-content> and Suggests Noncanonical Functions within the Pathway
ABSTRACT The unfolded protein response (UPR) is a signaling network that maintains homeostasis of the endoplasmic reticulum (ER). In the human-pathogenic fungus Aspergillus fumigatus, the UPR is initiated by activation of an endoribonuclease (RNase) domain in the ER transmembrane stress sensor IreA,...
Na minha lista:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020-10-01
|
| coleção: | mSphere |
| Assuntos: | |
| Acesso em linha: | https://journals.asm.org/doi/10.1128/mSphere.00879-20 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|