Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in <it>Aspergillus niger</it> reveals a coordinated cellular response to counteract ER stress

<p>Abstract</p> <p>Background</p> <p>HacA/Xbp1 is a conserved bZIP transcription factor in eukaryotic cells which regulates gene expression in response to various forms of secretion stress and as part of secretory cell differentiation. In the present study, we replaced the endogenous <it>hacA</it> g...

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Detalhes bibliográficos

Principais autores:	Carvalho Neuza DSP, Jørgensen Thomas R, Arentshorst Mark, Nitsche Benjamin M, van den Hondel Cees AMJJ, Archer David B, Ram Arthur FJ
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2012-07-01
coleção:	BMC Genomics
Assuntos:	HacA Unfolded protein response Secretion stress RESS XBP1 <it>Aspergillus niger</it> Protein secretion
Acesso em linha:	http://www.biomedcentral.com/1471-2164/13/350
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