Neuromuscular Mechanisms and Oxidative Stress in Skeletal Muscle Atrophy: Emerging Stem Cell and Gene-Based Therapeutic Strategies

Skeletal muscle atrophy emerges from intertwined neuromuscular and metabolic failures, in which neuromuscular junction destabilization, excitation contraction coupling defects, and mitochondrial dysfunction collectively intensify calcium dysregulation and drive the accumulation of reactive oxygen an...

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Detalhes bibliográficos

Principais autores:	Sathish Kumar Gunasekaran, Mandam Amzad Khan, Mehwish Mirza, Santhosh Shanthi Bhupathi, Mohamed Sheik Tharik Abdul Azeeze
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-02-01
Colecção:	Muscles
Assuntos:	skeletal muscle atrophy neuromuscular junction mitochondrial dysfunction ubiquitin-proteasome system FOXO NF-κB
Acesso em linha:	https://www.mdpi.com/2813-0413/5/1/13
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