Neuromuscular Mechanisms and Oxidative Stress in Skeletal Muscle Atrophy: Emerging Stem Cell and Gene-Based Therapeutic Strategies

Skeletal muscle atrophy emerges from intertwined neuromuscular and metabolic failures, in which neuromuscular junction destabilization, excitation contraction coupling defects, and mitochondrial dysfunction collectively intensify calcium dysregulation and drive the accumulation of reactive oxygen an...

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Autors principals:	Sathish Kumar Gunasekaran, Mandam Amzad Khan, Mehwish Mirza, Santhosh Shanthi Bhupathi, Mohamed Sheik Tharik Abdul Azeeze
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-02-01
Col·lecció:	Muscles
Matèries:	skeletal muscle atrophy neuromuscular junction mitochondrial dysfunction ubiquitin-proteasome system FOXO NF-κB
Accés en línia:	https://www.mdpi.com/2813-0413/5/1/13
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