Functional exosome-mediated co-delivery of doxorubicin and hydrophobically modified microRNA 159 for triple-negative breast cancer therapy

Abstract Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological information between cells. However, Exo are limited in terms of their abilities to target specific recipient cell types. We developed a strategy to isolate Exo exhibiting increased binding to integrin α...

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主要な著者:	Chunai Gong, Jing Tian, Zhuo Wang, Yuan Gao, Xin Wu, Xueying Ding, Lei Qiang, Guorui Li, Zhimin Han, Yongfang Yuan, Shen Gao
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2019-09-01
シリーズ:	Journal of Nanobiotechnology
主題:	Exosome MicroRNA 159 Doxorubicin Triple-negative breast cancer Co-delivery
オンライン･アクセス:	http://link.springer.com/article/10.1186/s12951-019-0526-7
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